Role of Mitofusin 2 in the Renal Stress Response
Role of Mitofusin 2 in the Renal Stress Response
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The role of mitofusin 2 (MFN2), a key regulator of mitochondrial morphology and function in the renal stress response is unknown. To assess its role, the MFN2 floxed gene was conditionally deleted in the kidney of mice (MFN2 cKO) by Pax2 promoter driven Cre expression (Pax2Cre). MFN2 cKO caused severe mitochondrial fragmentation in renal epithelial...
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Full title
Role of Mitofusin 2 in the Renal Stress Response
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TN_cdi_plos_journals_1323441665
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323441665
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0031074
