Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Familie...
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families
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Author / Creator
Cruchaga, Carlos , Chakraverty, Sumitra , Mayo, Kevin , Vallania, Francesco L. M. , Mitra, Robi D. , Faber, Kelley , Williamson, Jennifer , Bird, Tom , Diaz-Arrastia, Ramon , Foroud, Tatiana M. , Boeve, Bradley F. , Graff-Radford, Neill R. , St. Jean, Pamela , Lawson, Michael , Ehm, Margaret G. , Mayeux, Richard , Goate, Alison M. , for the NIA-LOAD/NCRAD Family Study Consortium and NIA-LOAD/NCRAD Family Study Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Pathogenic mutations in APP, PSEN1, PSEN2, MAPT and GRN have previously been linked to familial early onset forms of dementia. Mutation screening in these genes has been performed in either very small series or in single families with late onset AD (LOAD). Similarly, studies in single families have reported mutations in MAPT and GRN associated with...
Alternative Titles
Full title
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families
Authors, Artists and Contributors
Author / Creator
Chakraverty, Sumitra
Mayo, Kevin
Vallania, Francesco L. M.
Mitra, Robi D.
Faber, Kelley
Williamson, Jennifer
Bird, Tom
Diaz-Arrastia, Ramon
Foroud, Tatiana M.
Boeve, Bradley F.
Graff-Radford, Neill R.
St. Jean, Pamela
Lawson, Michael
Ehm, Margaret G.
Mayeux, Richard
Goate, Alison M.
for the NIA-LOAD/NCRAD Family Study Consortium
NIA-LOAD/NCRAD Family Study Consortium
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1323455129
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323455129
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0031039
