Ameliorated ConA-induced hepatitis in the absence of PKC-theta
Ameliorated ConA-induced hepatitis in the absence of PKC-theta
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Scope and Contents
Contents
Severe liver injury that occurs when immune cells mistakenly attack an individual's own liver cells leads to autoimmune hepatitis. In mice, acute hepatitis can be induced by concanavalin A (ConA) treatment, which causes rapid activation of CD1d-positive natural killer (NK) T cells. These activated NKT cells produce large amounts of cytokines, which...
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Full title
Ameliorated ConA-induced hepatitis in the absence of PKC-theta
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TN_cdi_plos_journals_1323559256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323559256
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0031174