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Ameliorated ConA-induced hepatitis in the absence of PKC-theta

Ameliorated ConA-induced hepatitis in the absence of PKC-theta

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323559256

Ameliorated ConA-induced hepatitis in the absence of PKC-theta

About this item

Full title

Ameliorated ConA-induced hepatitis in the absence of PKC-theta

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-02, Vol.7 (2), p.e31174

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Severe liver injury that occurs when immune cells mistakenly attack an individual's own liver cells leads to autoimmune hepatitis. In mice, acute hepatitis can be induced by concanavalin A (ConA) treatment, which causes rapid activation of CD1d-positive natural killer (NK) T cells. These activated NKT cells produce large amounts of cytokines, which...

Alternative Titles

Full title

Ameliorated ConA-induced hepatitis in the absence of PKC-theta

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1323559256

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323559256

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0031174

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