Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral...
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by a progressive loss of lower motor neurons in the spinal cord. The incretin hormone, glucagon-like peptide-1 (GLP-1), facilitates insulin signaling, and the long acting GLP-1 receptor agonist exendin-4 (Ex-4) is currently used as an anti-diabetic drug. GL...
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Full title
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis
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TN_cdi_plos_journals_1323851125
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323851125
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0032008
