Role of Position 627 of PB2 and the Multibasic Cleavage Site of the Hemagglutinin in the Virulence o...
Role of Position 627 of PB2 and the Multibasic Cleavage Site of the Hemagglutinin in the Virulence of H5N1 Avian Influenza Virus in Chickens and Ducks
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Highly pathogenic H5N1 avian influenza viruses have caused major disease outbreaks in domestic and free-living birds with transmission to humans resulting in 59% mortality amongst 564 cases. The mutation of the amino acid at position 627 of the viral polymerase basic-2 protein (PB2) from glutamic acid (E) in avian isolates to lysine (K) in human is...
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Full title
Role of Position 627 of PB2 and the Multibasic Cleavage Site of the Hemagglutinin in the Virulence of H5N1 Avian Influenza Virus in Chickens and Ducks
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TN_cdi_plos_journals_1323854988
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323854988
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030960
