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Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration a...

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323977626

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

About this item

Full title

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-03, Vol.7 (3), p.e33003-e33003

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recent evidence suggests that the observed clinical distinctions between lung tumors in smokers and never smokers (NS) extend beyond specific gene mutations, such as EGFR, EML4-ALK, and KRAS, some of which have been translated into targeted therapies. However, the molecular alterations identified thus far cannot explain all of the clinical and biol...

Alternative Titles

Full title

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1323977626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323977626

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0033003

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