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Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

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Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324394854

Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

About this item

Full title

Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

Author / Creator

Glas, Jürgen , Seiderer, Julia , Wagner, Johanna , Olszak, Torsten , Fries, Christoph , Tillack, Cornelia , Friedrich, Matthias , Beigel, Florian , Stallhofer, Johannes , Steib, Christian , Wetzke, Martin , Göke, Burkhard , Ochsenkühn, Thomas , Diegelmann, Julia , Czamara, Darina and Brand, Stephan

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-03, Vol.7 (3), p.e34349-e34349

Language

English

Formats

Articles

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

IL12B encodes the p40 subunit of IL-12, which is also part of IL-23. Recent genome-wide association studies identified IL12B and IL23R as susceptibility genes for inflammatory bowel disease (IBD). However, the phenotypic effects and potential gene-gene interactions of IL12B variants are largely unknown.
We analyzed IL12B gene variants regarding...

Alternative Titles

Full title

Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

Authors, Artists and Contributors

Author / Creator

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Record Identifier

TN_cdi_plos_journals_1324394854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324394854

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0034349

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