PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Coliti...
PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
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Author / Creator
Glas, Jürgen , Wagner, Johanna , Seiderer, Julia , Olszak, Torsten , Wetzke, Martin , Beigel, Florian , Tillack, Cornelia , Stallhofer, Johannes , Friedrich, Matthias , Steib, Christian , Göke, Burkhard , Ochsenkühn, Thomas , Karbalai, Nazanin , Diegelmann, Julia , Czamara, Darina and Brand, Stephan
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD). However, the exact role of PTPN2 in Crohn's disease (CD) and ulcerative colitis (UC) and its phenotypic effect are unclear. We therefore performed a detailed genotype-phenotype and epista...
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PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
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TN_cdi_plos_journals_1324434525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324434525
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0033682
