Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion
Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is overexpressed in various cancerous tissues but its role in carcinogenesis has not been established. Here, we report that gremlin-1 binds various cancer cell lines and this interaction is inhibited by our newly developed gremlin-1 antibody, GRE1. Gremlin-1 binding to cancer cells was unaff...
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Full title
Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion
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TN_cdi_plos_journals_1324444038
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324444038
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0035100
