Log in to save to my catalogue

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery wit...

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324444125

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass

About this item

Full title

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-04, Vol.7 (4), p.e35070-e35070

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Cardiopulmonary bypass (CPB) surgery initiates a controlled systemic inflammatory response characterized by a cytokine storm, monocytosis and transient monocyte activation. However, the responsiveness of monocytes to Toll-like receptor (TLR)-mediated activation decreases throughout the postoperative course. The purpose of this study was to identify...

Alternative Titles

Full title

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1324444125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324444125

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0035070

How to access this item