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Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mous...

Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mous...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324447695

Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mouse and Human CD4 T Cells

About this item

Full title

Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mouse and Human CD4 T Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-04, Vol.7 (4), p.e35466

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Certain parasites have evolved to evade the immune response and establish chronic infections that may persist for many years. T cell responses in these conditions become muted despite ongoing infection. Upregulation of surface receptors with inhibitory properties provides an immune cell-intrinsic mechanism that, under conditions of chronic infectio...

Alternative Titles

Full title

Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mouse and Human CD4 T Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1324447695

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324447695

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0035466

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