CRISPR interference directs strand specific spacer acquisition
CRISPR interference directs strand specific spacer acquisition
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders. In Escherichia coli, transcripts of these loci are cleaved into small RNAs and utilized by the Cascade complex to b...
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Full title
CRISPR interference directs strand specific spacer acquisition
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TN_cdi_plos_journals_1324595718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324595718
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0035888