MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The genome-wide association study (GWAS) approach has discovered hundreds of genetic variants associated with diseases and quantitative traits. However, despite clinical overlap and statistical correlation between many phenotypes, GWAS are generally performed one-phenotype-at-a-time. Here we compare the performance of modelling multiple phenotypes...
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Full title
MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
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TN_cdi_plos_journals_1324605026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324605026
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0034861
