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Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation

Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324610053

Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation

About this item

Full title

Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-05, Vol.7 (5), p.e36632-e36632

Language

English

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Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

The oxidative process of LDL particles generates molecules which are structurally similar to platelet-activating factor (PAF), and some effects of oxidized LDL (oxLDL) have been shown to be dependent on PAF receptor (PAFR) activation. In a previous study, we showed that PAFR is required for upregulation of CD36 and oxLDL uptake. In the present stud...

Alternative Titles

Full title

Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation

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Record Identifier

TN_cdi_plos_journals_1324610053

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324610053

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0036632

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