Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of diff...
Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development
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Author / Creator
Lockwood, William W , Wilson, Ian M , Coe, Bradley P , Chari, Raj , Pikor, Larissa A , Thu, Kelsie L , Solis, Luisa M , Nunez, Maria I , Behrens, Carmen , Yee, John , English, John , Murray, Nevin , Tsao, Ming-Sound , Minna, John D , Gazdar, Adi F , Wistuba, Ignacio I , MacAulay, Calum E , Lam, Stephen and Lam, Wan L
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
For therapeutic purposes, non-small cell lung cancer (NSCLC) has traditionally been regarded as a single disease. However, recent evidence suggest that the two major subtypes of NSCLC, adenocarcinoma (AC) and squamous cell carcinoma (SqCC) respond differently to both molecular targeted and new generation chemotherapies. Therefore, identifying the m...
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Full title
Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development
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TN_cdi_plos_journals_1324612095
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1324612095
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0037775