Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course...
Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Disruption of circadian rhythm is believed to play a critical role in cancer development. Cryptochrome 1 (CRY1) is a core component of the mammalian circadian clock and we have previously shown its deregulated expression in a subgroup of patients with chronic lymphocytic leukemia (CLL). Using real-time RT-PCR in a cohort of 76 CLL patients and 35 n...
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Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia
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TN_cdi_plos_journals_1325007742
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325007742
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0034347
