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Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325022022

Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

About this item

Full title

Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-05, Vol.7 (5), p.e37823-e37823

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The Dishevelled (Dvl) and Dishevelled-associated activator of morphogenesis 1 (Daam1) pathway triggered by Wnt5a regulates cellular polarity during development and tissue homoeostasis. However, Wnt5a signaling in breast cancer progression remains poorly defined.
We showed here that Wnt5a activated Dvl2, Daam1 and RhoA, and promoted migration of...

Alternative Titles

Full title

Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1325022022

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325022022

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0037823

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