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Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resul...

Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325026932

Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

About this item

Full title

Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-06, Vol.7 (6), p.e38889-e38889

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fungal components have been shown very effective in generating Th17 responses. We investigated whether exposure to a minute amount of C. albicans in the arthritic joint altered the local cytokine environment, leading to enhanced Th17 expansion and resulting in a more destructive arthritis.
Chronic SCW arthritis was induced by repeated injection...

Alternative Titles

Full title

Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1325026932

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325026932

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0038889

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