Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Diffe...
Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Alemtuzumab is a monoclonal antibody that targets cell surface CD52 and is effective in depleting lymphocytes by cytolytic effects in vivo. Although the cytolytic effects of alemtuzumab are dependent on the density of CD52 antigen on cells, there is scant information regarding the expression levels of CD52 on different cell types. In this study, CD...
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Full title
Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis
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TN_cdi_plos_journals_1325027001
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325027001
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0039416
