Krüppel-like factor 8 is a new Wnt/beta-catenin signaling target gene and regulator in hepatocellula...
Krüppel-like factor 8 is a new Wnt/beta-catenin signaling target gene and regulator in hepatocellular carcinoma
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Author / Creator
Yang, Tian , Cai, Sheng-Yun , Zhang, Jin , Lu, Jun-Hua , Lin, Chuan , Zhai, Jian , Wu, Meng-Chao and Shen, Feng
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Krüppel-like factor 8 (KLF8) plays important role in cell cycle and oncogenic transformation. Here we report the mechanisms by which KLF8 crosstalks with Wnt/β-catenin signaling pathway and regulates hepatocellular carcinoma (HCC) cells proliferation. We show that overexpression of KLF8 and nucleus accumulation of β-catenin in the human HCC samples...
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Full title
Krüppel-like factor 8 is a new Wnt/beta-catenin signaling target gene and regulator in hepatocellular carcinoma
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TN_cdi_plos_journals_1325039573
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325039573
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0039668