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Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early P...

Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325045085

Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early Promoters at Their Authentic Loci in MVA

About this item

Full title

Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early Promoters at Their Authentic Loci in MVA

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-06, Vol.7 (6), p.e40167-e40167

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

CD8(+) T cell responses to vaccinia virus are directed almost exclusively against early gene products. The attenuated strain modified vaccinia virus Ankara (MVA) is under evaluation in clinical trials of new vaccines designed to elicit cellular immune responses against pathogens including Plasmodium spp., M. tuberculosis and HIV-1. All of these rec...

Alternative Titles

Full title

Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early Promoters at Their Authentic Loci in MVA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1325045085

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325045085

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0040167

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