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Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse...

Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325436048

Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection

About this item

Full title

Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-07, Vol.7 (7), p.e40499

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in infants. Reduced CD8 T-cells and negligible interferon gamma (IFNγ) in the airway are associated with severe infant RSV disease, yet there is an abundance of alveolar macrophages (AM) and neutrophils. However, it is unclear, based on our current understanding...

Alternative Titles

Full title

Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1325436048

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1325436048

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0040499

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