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Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synth...

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326196412

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression

About this item

Full title

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-06, Vol.7 (6), p.e39501-e39501

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The main challenge in addressing the role of DNA methylation in human behaviour is the fact that the brain is inaccessible to epigenetic analysis in living humans. Using positron emission tomography (PET) measures of brain serotonin (5-HT) synthesis, we found in a longitudinal sample that adult males with high childhood-limited aggression (C-LHPA)...

Alternative Titles

Full title

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326196412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326196412

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0039501

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