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Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Gliob...

Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Gliob...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326218034

Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma

About this item

Full title

Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-07, Vol.7 (7), p.e40567

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Glioma is the most aggressive tumor of the brain and the most efficient treatments are based on radiotherapy. However, tumors are often resistant to radiotherapy due to an enhanced DNA repair activity. Short and stabilized DNA molecules (Dbait) have recently been proposed as an efficient strategy to inhibit DNA repair in tumor.
The distribution...

Alternative Titles

Full title

Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326218034

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326218034

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0040567

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