Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Polo-like kinase 4 (PLK4), belonging to serine/threonine kinase family, is critical for centriole replication and cell cycle progression. PLK4 has been proposed as a tumor suppressor in hepatocellular carcinoma (HCC). However, its expression and significance in HCC have not been well studied. In the present study, we found that PLK4 was markedly do...
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Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
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TN_cdi_plos_journals_1326219787
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326219787
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0041293