Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways
Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The development of the basic architecture of branching tubules enclosing a central lumen that characterizes most epithelial organs crucially depends on the apico-basolateral polarization of epithelial cells. Signals from the extracellular matrix control the orientation of the apical surface, so that it faces the lumen interior, opposite to cell-mat...
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Full title
Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways
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TN_cdi_plos_journals_1326223616
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223616
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0041039