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Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways

Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223616

Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways

About this item

Full title

Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-07, Vol.7 (7), p.e41039

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The development of the basic architecture of branching tubules enclosing a central lumen that characterizes most epithelial organs crucially depends on the apico-basolateral polarization of epithelial cells. Signals from the extracellular matrix control the orientation of the apical surface, so that it faces the lumen interior, opposite to cell-mat...

Alternative Titles

Full title

Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326223616

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326223616

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0041039

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