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FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding prote...

FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding prote...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326226689

FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway

About this item

Full title

FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e42456-e42456

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fork-head box protein A1 (FOXA1) is a "pioneer factor" that is known to bind to the androgen receptor (AR) and regulate the transcription of AR-specific genes. However, the precise role of FOXA1 in prostate cancer (PC) remains unknown. In this study, we report that FOXA1 plays a critical role in PC cell proliferation. The expression of FOXA1 was hi...

Alternative Titles

Full title

FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326226689

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326226689

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0042456

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