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Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate...

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238543

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

About this item

Full title

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e43031

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Retinoic acid inducible gene I (RIG-I)-like receptors (RLRs) function as cytoplasmic sensors for viral RNA to initiate antiviral responses including type I interferon (IFN) production. It has been unclear how RIG-I encounters and senses viral RNA. To address this issue, we examined intracellular localization of RIG-I in response to viral infection...

Alternative Titles

Full title

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326238543

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238543

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0043031

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