Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate...
Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Retinoic acid inducible gene I (RIG-I)-like receptors (RLRs) function as cytoplasmic sensors for viral RNA to initiate antiviral responses including type I interferon (IFN) production. It has been unclear how RIG-I encounters and senses viral RNA. To address this issue, we examined intracellular localization of RIG-I in response to viral infection...
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Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity
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TN_cdi_plos_journals_1326238543
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326238543
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0043031