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miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326512786

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

About this item

Full title

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e44532

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In this work, we assessed whether SERPINE1 expression could be under the influence of microRNAs (miRNAs) predicted to bind the SERPINE1 3'UTR region. We specifically focused on the 3'UTR region harboring a common polymorphism, rs1050955, that have been found associated to SERPINE1 monocyte expression, and investigated whether the presence of differ...

Alternative Titles

Full title

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326512786

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326512786

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0044532

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