Antibody constant region peptides can display immunomodulatory activity through activation of the De...
Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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We previously reported that a synthetic peptide with sequence identical to a CDR of a mouse monoclonal antibody specific for difucosyl human blood group A exerted an immunomodulatory activity on murine macrophages. It was therapeutic against systemic candidiasis without possessing direct candidacidal properties. Here we demonstrate that a selected...
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Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway
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TN_cdi_plos_journals_1326543576
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326543576
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0043972