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Antibody constant region peptides can display immunomodulatory activity through activation of the De...

Antibody constant region peptides can display immunomodulatory activity through activation of the De...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326543576

Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway

About this item

Full title

Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e43972-e43972

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We previously reported that a synthetic peptide with sequence identical to a CDR of a mouse monoclonal antibody specific for difucosyl human blood group A exerted an immunomodulatory activity on murine macrophages. It was therapeutic against systemic candidiasis without possessing direct candidacidal properties. Here we demonstrate that a selected...

Alternative Titles

Full title

Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326543576

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326543576

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0043972

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