Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibr...
Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Type I collagen is the most abundant protein in the human body. Its excessive synthesis results in fibrosis of various organs. Fibrosis is a major medical problem without an existing cure. Excessive synthesis of type I collagen in fibrosis is primarily due to stabilization of collagen mRNAs. We recently reported that intermediate filaments composed...
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Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo
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TN_cdi_plos_journals_1326543834
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326543834
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0042989
