Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor...
Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients
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Author / Creator
Lodola, Francesco , Laforenza, Umberto , Bonetti, Elisa , Lim, Dmitry , Dragoni, Silvia , Bottino, Cinzia , Ong, Hwei Ling , Guerra, Germano , Ganini, Carlo , Massa, Margherita , Manzoni, Mariangela , Ambudkar, Indu S , Genazzani, Armando A , Rosti, Vittorio , Pedrazzoli, Paolo , Tanzi, Franco , Moccia, Francesco and Porta, Camillo
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Endothelial progenitor cells (EPCs) may be recruited from bone marrow to sustain tumor vascularisation and promote the metastatic switch. Understanding the molecular mechanisms driving EPC proliferation and tubulogenesis could outline novel targets for alternative anti-angiogenic treatments. Store-operated Ca(2+) entry (SOCE), which is activated by...
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Full title
Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients
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TN_cdi_plos_journals_1326544877
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326544877
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0042541
