Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2
Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
The angiopoietins (ANGPT) are ligands for the endothelial cell (EC) receptor tyrosine kinase, Tie2. Angpt-1 is a Tie2 agonist that promotes vascular maturation and stabilization, whereas Angpt-2 is a partial agonist/antagonist involved in the initiation of postnatal angiogenesis. Therefore, we hypothesized that overexpression of Angpt-2 would be mo...
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Full title
Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2
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TN_cdi_plos_journals_1326551017
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326551017
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0043568
