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Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overex...

Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326558435

Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression

About this item

Full title

Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-10, Vol.7 (10), p.e47134-e47134

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of the MMP inhibitor TIMP-1. First we studied 47 vein...

Alternative Titles

Full title

Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326558435

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326558435

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0047134

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