NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage...
NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The human embryonic, fetal and adult β-like globin genes provide a paradigm for tissue- and developmental stage-specific gene regulation. The fetal γ-globin gene is expressed in fetal erythroid cells but is repressed in adult erythroid cells. The molecular mechanism underlying this transcriptional switch during erythroid development is not complete...
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Full title
NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene
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TN_cdi_plos_journals_1326558479
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326558479
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047175
