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An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabili...

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabili...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326559220

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer

About this item

Full title

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-10, Vol.7 (10), p.e47086-e47086

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Targeted therapies have been used to combat many tumor types; however, few have effectively improved the overall survival in women with epithelial ovarian cancer, begging for a better understanding of this deadly disease and identification of essential drivers of tumorigenesis that can be targeted effectively. Therefore, we used a loss-of-function...

Alternative Titles

Full title

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326559220

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326559220

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0047086

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