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Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer

Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326560314

Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer

About this item

Full title

Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-10, Vol.7 (10), p.e46737-e46737

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Survivin is expressed in prostate cancer (PCa), and its downregulation sensitizes PCa cells to chemotherapeutic agents in vitro and in vivo. Small membrane-bound vesicles called exosomes, secreted from the endosomal membrane compartment, contain RNA and protein that they readily transport via exosome internalization into recipient cells. Recent pro...

Alternative Titles

Full title

Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326560314

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326560314

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0046737

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