Measurements of CFTR-Mediated Cl− Secretion in Human Rectal Biopsies Constitute a Robust Biomarker f...
Measurements of CFTR-Mediated Cl− Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis
About this item
Full title
Author / Creator
Sousa, Marisa , Servidoni, Maria F. , Vinagre, Adriana M. , Ramalho, Anabela S. , Bonadia, Luciana C. , Felício, Verónica , Ribeiro, Maria A. , Uliyakina, Inna , Marson, Fernando A. , Kmit, Arthur , Cardoso, Silvia R. , Ribeiro, José D. , Bertuzzo, Carmen S. , Sousa, Lisete , Kunzelmann, Karl , Ribeiro, Antônio F. and Amaral, Margarida D.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Cystic Fibrosis (CF) is caused by ∼1,900 mutations in the CF transmembrane conductance regulator (CFTR) gene encoding for a cAMP-regulated chloride (Cl(-)) channel expressed in several epithelia. Clinical features are dominated by respiratory symptoms, but there is variable organ involvement thus causing diagnostic dilemmas, especially for non-clas...
Alternative Titles
Full title
Measurements of CFTR-Mediated Cl− Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis
Authors, Artists and Contributors
Author / Creator
Servidoni, Maria F.
Vinagre, Adriana M.
Ramalho, Anabela S.
Bonadia, Luciana C.
Felício, Verónica
Ribeiro, Maria A.
Uliyakina, Inna
Marson, Fernando A.
Kmit, Arthur
Cardoso, Silvia R.
Ribeiro, José D.
Bertuzzo, Carmen S.
Sousa, Lisete
Kunzelmann, Karl
Ribeiro, Antônio F.
Amaral, Margarida D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1326560417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326560417
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047708
