Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free...
Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
PHD fingers represent one of the largest families of epigenetic readers capable of decoding post-translationally modified or unmodified histone H3 tails. Because of their direct involvement in human pathologies they are increasingly considered as a potential therapeutic target. Several PHD/histone-peptide structures have been determined, however re...
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Full title
Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study
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TN_cdi_plos_journals_1326560838
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326560838
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0046902
