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LH and hCG action on the same receptor results in quantitatively and qualitatively different intrace...

LH and hCG action on the same receptor results in quantitatively and qualitatively different intrace...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326720469

LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling

About this item

Full title

LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-10, Vol.7 (10), p.e46682

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and molecular response. This study compares for the first time the activation of cell-signalling pathways and gene expression in response to hLH and hCG. Using recombinant hLH and recombinant hC...

Alternative Titles

Full title

LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326720469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326720469

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0046682

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