CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease
CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Progressive mitochondrial dysfunction contributes to neuronal degeneration in age-mediated disease. An essential regulator of mitochondrial function is the deacetylase, sirtuin 3 (SIRT3). Here we investigate a role for CNS Sirt3 in mitochondrial responses to reactive oxygen species (ROS)- and Alzheimer's disease (AD)-mediated stress. Pharmacologica...
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CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease
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TN_cdi_plos_journals_1326725250
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326725250
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0048225
