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Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative...

Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326746535

Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

About this item

Full title

Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-11, Vol.7 (11), p.e50062-e50062

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alternative Lengthening of Telomeres (ALT) is a non-telomerase mechanism of telomere lengthening that occurs in about 10% of cancers overall and is particularly common in astrocytic brain tumors and specific types of sarcomas. Somatic cell hybridization analyses have previously shown that normal telomerase-negative fibroblasts and telomerase-positi...

Alternative Titles

Full title

Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1326746535

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326746535

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0050062

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