Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative...
Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Alternative Lengthening of Telomeres (ALT) is a non-telomerase mechanism of telomere lengthening that occurs in about 10% of cancers overall and is particularly common in astrocytic brain tumors and specific types of sarcomas. Somatic cell hybridization analyses have previously shown that normal telomerase-negative fibroblasts and telomerase-positi...
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Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres
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TN_cdi_plos_journals_1326746535
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326746535
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ISSN
1932-6203
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1932-6203
DOI
10.1371/journal.pone.0050062