Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex:...
Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The membrane associated guanylate kinase (MAGUK) family member, human Discs Large 1 (hDlg1) uses a PDZ domain array to interact with the polarity determinant, the Adenomatous Polyposis Coli (APC) microtubule plus end binding protein. The hDLG1-APC complex mediates a dynamic attachment between microtubule plus ends and polarized cortical determinant...
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Full title
Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering
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TN_cdi_plos_journals_1326746557
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326746557
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0050097
