Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoti...
Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoting the invasiveness of prostate cancer cells
About this item
Full title
Author / Creator
Wang, Hongyan , Fan, Liangsheng , Wei, Juncheng , Weng, Yanjie , Zhou, Li , Shi, Ying , Zhou, Wenjuan , Ma, Ding and Wang, Changyu
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
Subjects
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Scope and Contents
Contents
Human metastasis-associated gene 1 (MTA1) is highly associated with the metastasis of prostate cancer; however, the molecular functions of MTA1 that facilitate metastasis remain unclear. In this study, we demonstrate that the silencing of MTA1 by siRNA treatment results in the upregulation of E-cadherin expression by the phosphorylation of AKT (p-A...
Alternative Titles
Full title
Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoting the invasiveness of prostate cancer cells
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1326751574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1326751574
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0046888
