Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KR...
Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The employment of anti-epidermal growth factor receptor (EGFR) antibodies represents a backbone of the therapeutic options for the treatment of metastatic colorectal cancer (mCRC). However, this therapy is poorly effective or ineffective in unselected patients. Mutations in KRAS, BRAF and PIK3CA genes have recently emerged as the best predictive fa...
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Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations
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TN_cdi_plos_journals_1327103908
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327103908
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0041347
