A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity
A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The HIV vaccine strategy that, to date, generated immune protection consisted of a prime-boost regimen using a canarypox vector and an HIV envelope protein with alum, as shown in the RV144 trial. Since the efficacy was weak, and previous HIV vaccine trials designed to generate antibody responses failed, we hypothesized that generation of T cell res...
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Full title
A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity
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TN_cdi_plos_journals_1327117589
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327117589
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0042163
