Oxidative Stress-Induced Glomerular Mineralocorticoid Receptor Activation Limits the Benefit of Salt...
Oxidative Stress-Induced Glomerular Mineralocorticoid Receptor Activation Limits the Benefit of Salt Reduction in Dahl Salt-Sensitive Rats
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Mineralocorticoid receptor (MR) antagonists attenuate renal injury in salt-sensitive hypertensive rats with low plasma aldosterone levels. We hypothesized that oxidative stress causes MR activation in high-salt-fed Dahl salt-sensitive rats. Furthermore, we determined if MR activation persisted and induced renal injury, even after switching from a h...
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Full title
Oxidative Stress-Induced Glomerular Mineralocorticoid Receptor Activation Limits the Benefit of Salt Reduction in Dahl Salt-Sensitive Rats
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TN_cdi_plos_journals_1327118446
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327118446
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0041896
