MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-defici...
MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The X-linked Mecp2 is a known interpreter of epigenetic information and mutated in Rett syndrome, a complex neurological disease. MeCP2 recruits HDAC complexes to chromatin thereby modulating gene expression and, importantly regulates higher order heterochromatin structure. To address the effects of MeCP2 deficiency on heterochromatin organization...
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MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line
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TN_cdi_plos_journals_1327130815
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327130815
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047848
