Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprote...
Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Chronic inflammation and oxidative stress play fundamental roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). Previously, we reported that myeloperoxidase (MPO), an aggressive oxidant-generating neutrophil enzyme, is associated with NASH severity in man. We now investigated the hypothesis that MPO contributes to the development and...
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Full title
Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice
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TN_cdi_plos_journals_1327199382
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327199382
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0052411
