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Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231426

Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

About this item

Full title

Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e53216-e53216

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Imaging studies have demonstrated that ventilation during bronchoconstriction in subjects with asthma is patchy with large ventilation defective areas (Vdefs). Based on a theoretical model, we postulated that during bronchoconstriction, as smooth muscle force activation increases, a patchy distribution of ventilation should emerge, even in the pres...

Alternative Titles

Full title

Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327231426

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231426

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053216

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